Topiramate is an anticonvulsant has been prescribed to reduce the frequency of chronic migraine headaches.
Generic topamax is an anticonvulsant, and this class of compounds has previously been shown to reduce the frequency of chronic migraine headaches, though the randomised trial evidence base is limited. Topamax was first approved by the FDA to treat epilepsy in 1996. Topamax is also approved to treat migraines. The classic migraine involves being brought to the ground by the nausea, the sensitivity to light and sound, and the jackhammers that have taken up residence in your head for at least a couple of hours.
Topiramate at doses up to 100 mg daily significantly reduces the frequency of chronic migraine. The proportion of patients with at least 50% reduction in headache frequency is 46%, and 26% have at least 75% reduction in frequency. Compared with placebo, NNTs are 4.1 for a 50% reduction, and 6.2 for a 75% reduction.
Topamax is also used for: Adjunctive treatment for adults with Bipolar Disorder so when used with other meds it tests well, and Adjunctive treatment of children and adolescents with Bipolar Disorder. In Monotherapy for Bipolar Disorder, and another study here it's not that great used by itself for random bipolar patients, but more about that in the comments section. Topamax will do its usual thing of working great for half the people and really messing up the other half. Topamax is used for weight loss when you're not mentally interesting, where it failed utterly in the two clinical trials for dieting and it continues to mess people up to use it for dieting purposes.
Randomised trials comparing topiramate with placebo used any dose regimen of topiramate, in patients with chronic migraine headache (at least two episodes a month), used standard diagnostic classification, and was at least of four weeks duration. The main outcomes sought were the number or proportion of patients with migraine frequency reduced by at least 50%, and adverse events. Adverse events included parasthesia, fatigue, mood swings and anorexia, with about one patient in five discontinuing because of adverse events on topiramate.
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It's the currently the only modern anticonvulsant approved by the FDA that you can take by itself to treat tonic-clonic complex partial seziures and simple partial seizures. The best med on the market for temporal lobe dysfunctions. It really helps with the sensory integration problems in autism.
If you don't have a temporal lobe dysfunction or problems with other parts of your brain that Topamax hits, or you're at the wrong dosage, it will make you dumber than a box of rocks. If you're taking birth control pills for any reason at all and you start Topamax you need to contact your doctor.
Anticonvulsant drugs are used to control seizures in people with epilepsy. Epilepsy is not a single disease. It is a set of symptoms that may have different causes in different people.